项目
专利
论文 || 2024 || 2023 || 2022 || 2021之前

项目

  • 福建省自然科学基金面上项目，2025J01842，基于单细胞激酶活性推断的药物重定位研究，2025-05至2028-04，10万元，主持.
  • 福建医科大学高层次引进人才项目，XRCZX2024018，基于蛋白质组学的复杂疾病研究，2024.10-2029.09，40万， 主持.
  • 江苏省自然科学基金青年项目，BK20220316，Tau微管蛋白激酶2异常在非梗阻性无精子症中的作用与机制研究，2022.07-2025.06，20万元， 项目骨干.

专利

  • 郭雪江，李妍，司徒成昊，王兵. 一种基于深度学习提高单细胞蛋白质组鉴定覆盖率的方法，ZL202210331187.8.
  • 郭雪江，李妍，司徒成昊，王兵. 蛋白质亚细胞定位的空间蛋白质组学深度学习预测方法，ZL202210757754.6.
  • 郭雪江，李妍，司徒成昊，王兵. 蛋白质亚细胞迁移的时空蛋白质组学深度学习预测方法，ZL202311738077.4.

论文（第一作者为#，通讯作者为*）

2024

  • Wang B#, Zhang X, Han X, Hao B, Li Y, Guo X. TransGCN: a semi-supervised graph convolution network-based framework to infer protein translocations in spatio-temporal proteomics. Briefings in Bioinformatics. 2024 Jan 22;25(2):bbae055. (SCI一区, JCR Q1, 2023IF=6.8, 排名第一)
  • Sun H#, Han L#, Guo Y#, An H#, Wang B#, Zhang X, Li J, Jiang Y, Wang Y, Sun G, Zhu S, Tang S, Ge J, Chen M, Guo X, Wang Q. The global phosphorylation landscape of mouse oocytes during meiotic maturation. The EMBO Journal 2024 Oct;43(20):4752-4785. (SCI一区, JCR Q1, 2023IF=9.4, 共一第五)
  • Zhang X#, Tu H#, Zhou X#, Wang B, Guo Y, Situ C, Qi Y, Li* Y, Guo X*. Quantitative Phosphoproteomic Profiling of Mouse Sperm Maturation in Epididymis Revealed Kinases Important for Sperm Motility. Molecular & Cellular Proteomics. 2024 Aug;23(8):100810. (SCI一区, JCR Q1, 2023IF=6.1, 排名第四)
  • Guo Y#, Gao M#, Liu X#, Zhang H#, Wang Y, Yan T, Wang B, Han X, Qi Y, Zhu H, Situ C, Li Y, Guo X*. Single-Cell Multi-Omics Analysis of In Vitro Post-Ovulatory-Aged Oocytes Revealed Aging-Dependent Protein Degradation. Molecular & Cellular Proteomics. 2024 Nov 20;24(1):100882. (SCI一区, JCR Q1, 2023IF=6.1, 排名第四)
  • Hu Y#, Wang Y#, He Y#, Ye M, Yuan J, Ren C, Wang X, Wang S, Guo Y, Cao Q, Zhou S, Wang B, He A, Hu J, Guo X, Shu W, Huo R. Maternal KLF17 controls zygotic genome activation by acting as a messenger for RNA Pol II recruitment in mouse embryos. Developmental Cell. 2024 Mar 11;59(5):613-626. (SCI一区, JCR Q1, 2023IF=10.7, 排名第十二)

2023

  • Wang B#, Zhang X, Xu C, Han X, Wang Y, Situ C, Li Y, Guo X. DeepSP: A Deep Learning Framework for Spatial Proteomics. Journal of Proteome Research. 2023 Jul 7;22(7):2186-2198. (SCI二区, JCR Q1, 2022IF=4.4, 排名第一)
  • Han X#, Wang B, Situ C, Qi Y, Zhu H, Li Y, Guo X*. scapGNN: A graph neural network-based framework for active pathway and gene module inference from single-cell multi-omics data. PLoS Biology. 2023 Nov 13;21(11):e3002369. (SCI一区, JCR Q1, 2022IF=9.8, 排名第二)
  • Li X#, Liao M, Wang B, Zan X, Huo Y, Liu Y, Bao Z, Xu P, Liu W. A drug repurposing method based on inhibition effect on gene regulatory network. Computational and Structural Biotechnology Journal. 2023 Sep 9;21:4446-4455. (SCI二区, JCR Q1, 2022IF=6.0, 排名第三)
  • Yao Y#, Shi B, Zhang X, Wang X, Li S, Yao Y, Guo Y, Chen D, Wang B, Yuan Y, Sha J, Guo X. Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis. Journal of Biomedical Research. 2023 Dec 8;38(1):24-36. (SCI四区, JCR Q2, 2022IF=2.3, 排名第九)

2022

  • Wang B#, Wang Y#, Chen Y#, Gao M, Ren J, Guo Y, Situ C, Qi Y, Zhu H, Li Y, Guo X. DeepSCP: utilizing deep learning to boost single-cell proteome coverage. Briefings in Bioinformatics. 2022 Jul 18;23(4):bbac214. (SCI一区, JCR Q1, 2021IF=13.994, 共一第一)
  • Guo Y#, Cai L#, Liu X#, Ma L#, Zhang H#, Wang B, Qi Y, Liu J, Diao F, Sha J, Guo X*. Single-Cell Quantitative Proteomic Analysis of Human Oocyte Maturation Revealed High Heterogeneity in In Vitro-Matured Oocytes. Molecular & Cellular Proteomics. 2022 Aug;21(8):100267. (SCI一区, JCR Q1, 2021IF=7.381, 排名第六)
  • Li H#, Chen H#, Zhang X#, Qi Y#, Wang B, Cui Y, Ren J, Zhao Y, Chen Y, Zhu T, Wang Y, Yao L, Guo Y, Zhu H, Li Y, Situ C, Guo X*. Global phosphoproteomic analysis identified key kinases regulating male meiosis in mouse. Cellular and Molecular Life Sciences. 2022 Aug 5;79(8):467. (SCI一区, JCR Q1, 2021IF=9.207, 排名第五)
  • Cui C#, Qin H#, Zhu X#, Lu X, Wang B, Wang X, Wang J, Jiao J, Chu M, Wang C, Li M, Wang X, Wang D, Chen M*. Unsupervised machine learning reveals epicardial adipose tissue subtypes with distinct atrial fibrosis profiles in patients with persistent atrial fibrillation: A prospective 2-center cohort study. Heart Rhythm. 2022 Dec;19(12):2033-2041. (SCI二区, JCR Q1, 2021IF=7.381, 排名第五)

2021之前

  • 何鑫#, 张涛川, 黎易峰, 王兵. 基于 RF-DNN 的乳腺癌亚型诊断方法. 工业控制计算机, 2021, 34(7): 80-81. (科技核心, 排名第四)
  • Liu W#, Wang B, Fang G, Shi X, Xu P*. Study on the Differential Analysis of Alternative Splicing Based on the Median Value Jensen-Shannon Divergence. Journal of Electronics & Information Technology. 2020, 42(6):1392-1400. (EI, 排名第二)
  • Xu P#, Wang B, Fang G, Shi X, Liu W*. Analysis of Breast Cancer Subtypes Prediction Based on Alternative Splicing Disorders. Journal of Electronics & Information Technology, 2020, 42(6): 1348-1354. (EI, 排名第二)